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. 2017 Feb 25;4(3):e1295127. doi: 10.1080/23723556.2017.1295127

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Figure 2. — Potential applications of YAP immunohistochemistry in clinical practice as a diagnostic or a prognostic marker. Immunohistochemistry for YAP was performed at The Children's Mercy Hospital, Kansas City, Missouri on the Leica Bond instrument using an antibody against the nonphosphorylated protein (Santa Cruz, Dallas, Texas). A. Nuclear staining for YAP is identified in embryonal rhabdomyosarcoma cells, while the infiltrating lymphocytes are negative (x400). B. YAP immunoreactivity in nodular desmoplastic medulloblastoma. Nuclear staining is present in the internodular region (x200).