Table 2.
Identification of ECM proteins (SDS-urea Insoluble) increased by the treatment of TGF-β2 in human TM cells
| UniProtKB Accession Number | ECM proteins | TGF-β2/ control | Anova score (n=3) |
|---|---|---|---|
| P55001 | Isoform B of Microfibrillar-associated protein 2 | 5420.45 | 0.030310641 |
| P15502 | Isoform 1 of Elastin | 2383.03 | 0.000996696 |
| Q08380 | Galectin-3-binding protein | 345.54 | 0.031886199 |
| Q08397 | Lysyl oxidase homolog 1 | 103.72 | 0.003609312 |
| P08572 | Collagen alpha-2(IV) chain | 103.62 | 0.050572634 |
| Q15582 | Transforming growth factor-beta-induced protein ig-h3 | 89.32 | 0.010342166 |
| P35556-2 | Isoform 2 of Fibrillin-2 | 63.99 | 0.000896711 |
| P28300 | Protein-lysine 6-oxidase | 60.64 | 0.056805848 |
| P23142 | Fibulin-1 | 54.68 | 0.036896707 |
| Q9NR12 | Isoform 2 of PDZ and LIM domain protein 7 | 38.89 | 0.035390200 |
| Q05682 | Caldesmon | 30.07 | 0.010006786 |
| P15502- | Elastin | 23.97 | 3.24E-07 |
| P27658 | Collagen alpha-1(VIII) chain | 19.52 | 0.001247321 |
| O95084 | Serine protease 23 | 18.68 | 0.005377157 |
| P24821 | Isoform 4 of Tenascin | 17.86 | 0.020668783 |
| Q6ZMP0 | Thrombospondin type-1 domain-containing protein 4 | 17.40 | 0.002451091 |
| Q15063 | Periostin | 16.64 | 0.001791472 |
| P10909 | Isoform 4 of Clusterin | 16.61 | 0.00958499 |
| Q8CG19 | Latent-transforming growth factor beta-binding protein 1 | 15.81 | 0.008906995 |
| P02461 | Collagen alpha-1(III) chain | 12.05 | 0.000580960 |
| Q6S8J3 | POTE ankyrin domain family member E | 9.4 | 0.045704313 |
| P08493 | Matrix Gla protein | 9.26 | 0.027908934 |
| P21980 | Protein-glutamine gamma-glutamyltransferase 2 | 9.07 | 0.002020116 |
| P02452 | Collagen alpha-1(I) chain | 8.40 | 0.011448809 |
| P08123 | Collagen alpha-2(I) chain | 7.46 | 0.008255035 |
| P08670 | Vimentin | 6.06 | 0.011686546 |
| P68104 | Elongation factor 1-alpha 1 | 5.31 | 0.012505388 |
| Q8WX93 | Isoform 4 of Palladin | 4.84 | 0.008290409 |
| P35556-2 | Fibrillin-2 | 3.67 | 0.002732843 |
| P60709 | Actin, cytoplasmic 1 | 3.48 | 0.007046709 |
| Q9Y6C2 | EMILIN-1 | 3.17 | 0.005123759 |
| P02751 | Isoform 6 of Fibronectin | 2.6 | 0.002583220 |
| Q53GK6 | Beta actin variant (fragment) | 2.2 | 0.001481174 |
| Q5SZJ2 | Basement membrane-specific heparan sulfate proteoglycan core protein (Fragment) | 2.0 | 2.07E-05 |
| A8K9I5 | Beta-1,3-glucuronyltransferase 3 | 2.0 | 0.000945761 |