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. 2017 Jun 7;96(6):1325–1337. doi: 10.4269/ajtmh.16-0634

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©The American Society of Tropical Medicine and Hygiene

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Figure 7. — Avidity index vs. the N antibody titers by MN50 for dengue virus serotypes 1–4 at D56 (adapted according-to-protocol cohort for immunogenicity). 1 μg + alum indicates participants who received 1 μg/serotype/dose adjuvanted with alum; 4 μg + alum indicates participants who received 4 μg/serotype/dose adjuvanted with alum; 1 μg + AS01_E indicates participants who received 1 μg/serotype/dose adjuvanted with AS01_E; 1 μg + AS03_B indicates participants who received 1 μg/serotype/dose adjuvanted with AS03_B. DENV = dengue virus serotype; D56 = Day 56 (1 month post-dose 2); Loess = nonparametric local regression fit. According to the time point, the following cohorts were used to create the adapted according-to-protocol cohort for immunogenicity D56: for PRE, D28, D56: ATP cohort for immunogenicity; for M7: ATP cohort for immunogenicity M7 and for M13: ATP cohort for immunogenicity M13.