TABLE 3.
Statistical summary of exposure and age effects on alveolar growth and size
| Exposure | Age | HDMA | Ozone | HDMA + Ozone | Two-way ANOVA | |||||
|---|---|---|---|---|---|---|---|---|---|---|
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| HDMA(HD) vs. Ozone | ||||||||||
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| 3 months | 6 months | 3 months | 6 months | 3 months | 6 months | Age (months) in parenthesis HD OZONE | ||||
| Lobe Volume | NS | P < 0.001 | NS | NS | NS | NS | NS | 0.026 | NS | 0.009(6) |
| Number Alveoli | 0.020 | P < 0.001 | NS | NS | 0.041 | NS | 0.006 | NS | NS | P < 0.001(3) |
| Number-weighted alveolar volume | P < 0.001 | NS | NS | NS | 0.026 | NS | 0.002 | NS | NS | P < 0.001(3), P < 0.001(6) |
| Cv | P < 0.001 | NS | NS | NS | 0.017 | NS | 0.001 | NS | NS | P < 0.001(3), P < 0.001(6) |
| Ss Capillary | P < 0.001 | P < 0.001 | NS | NS | P < 0.001 | NS | 0.001 | NS | NS | P < 0.001(3) |