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. Author manuscript; available in PMC: 2018 Apr 7.
Published in final edited form as: J Proteome Res. 2017 Mar 8;16(4):1763–1772. doi: 10.1021/acs.jproteome.7b00024

Figure 3.

Figure 3

Analysis of exosomal protein content. Among 1559 quantified proteins, 1424 proteins had GO information. (a) The subcellular distribution shows that proteins from cytoplasm, plasma membrane, extracellular space, and nucleus account for 41.85, 23.10, 19.80, and 10.11%, respectively. (b) The functional analysis shows that those proteins are mainly enzyme (20.33%), transporter (9.07%), peptidase (7.44%), kinase (4.04%), transmembrane receptor (3.82%), and regulator (3.54%). (c) The pathway analysis shows that proteins involved in the immune response (33.24%), thrombosis (12.24%), metastasis (21.47%), and proliferation (7.06%) were enriched in our data set.