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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Proteomics. 2016 Dec;16(23):3042–3053. doi: 10.1002/pmic.201600057

Figure 1. Significant changes in the detergent insoluble brain proteome increase with pathological severity.

Figure 1

Volcano plots display the protein abundance (log2-fold-change) against the t-statistic (−log10(p-value)) for AsymAD/Control (left), MCI/Control (middle) and AD/Control (right). Red and green dots are differentially enriched or depleted proteins, respectively, whereas blue dots represent proteins that remain unchanged.