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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Proteomics. 2016 Dec;16(23):3042–3053. doi: 10.1002/pmic.201600057

Figure 3. Proteins and pathways increased in the detergent insoluble AD proteome.

Figure 3

(A) Venn diagram for 265 proteins determined to be significantly altered (±1.5 fold and p value <0.05) among the three pairwise comparisons AsymAD, MCI and AD versus control cases, respectively. (B) Gene ontology (GO) analysis of the significantly enriched proteins for AD/control in the insoluble proteome reveals biological processes (red), cellular components (green) and molecular functions (blue) significantly over-represented (Z>1.96 is equivalent to p<0.05; above black line).