Table 3.
Top differentially spliced protein-coding genes between PDAC and normal pancreas.
| Probe-set_ID | Transcript cluster_ID | Symbol | Definition | logFC (FIRMA) | Event | adj. P-Value |
|---|---|---|---|---|---|---|
| 3824875 | 3824874 | IFI30 | Interferon, gamma-inducible protein 30 | −11.93 | skipped | 6.42E-09 |
| 3861578 | 3861557 | LGALS4 | Lectin, galactoside-binding, soluble, 4 | −10.80 | skipped | 2.66E-08 |
| 2829950 | 2829947 | TGFBI | Transforming growth factor, beta-induced, 68kDa | −10.23 | skipped | 4.89E-09 |
| 2880347 | 2880292 | DPYSL3 | Dihydropyrimidinase-like 3 | −9.75 | skipped | 5.24E-14 |
| 3632030 | 3631964 | PKM2 | Pyruvate kinase, muscle | −9.71 | skipped | 9.00E-11 |
| 3119348 | 3119339 | LY6E | Lymphocyte antigen 6 complex, locus E | -9.57 | skipped | 4.96E-11 |
| 3405602 | 3405587 | GPRC5A | G protein-coupled receptor, family C, group 5, member A | −9.54 | skipped | 2.14E-15 |
| 2598263 | 2598261 | FN1 | Fibronectin 1 | −9.38 | skipped | 5.71E-08 |
| 3264344 | 3264326 | ACSL5 | Acyl-CoA synthetase long-chain family member 5 | −9.28 | skipped | 4.21E-15 |
| 3058819 | 3058759 | SEMA3C | Semaphorin-3C | −9.22 | skipped | 3.30E-11 |
| 3762200 | 3762198 | COL1A1 | Collagen, type I, alpha 1 | 13.64 | included | 3.86E-14 |
| 3013163 | 3013054 | COL1A2 | Collagen, type I, alpha 2 | 9.50 | included | 4.50E-11 |
| 3013162 | 3013054 | COL1A2 | Collagen, type I, alpha 2 | 8.44 | included | 7.09E-11 |
| 3762202 | 3762198 | COL1A1 | Collagen, type I, alpha 1 | 6.87 | included | 3.35E-13 |
| 3762203 | 3762198 | COL1A1 | Collagen, type I, alpha 1 | 6.35 | included | 4.02E-08 |
| 2535909 | 2535859 | CAPN10 | Calpain 10 | 6.30 | included | 7.07E-09 |
| 3351230 | 3351200 | TMPRSS4 | Transmembrane protease, serine 4 | 5.89 | included | 1.38E-09 |
| 3193625 | 3193482 | COL5A1 | Collagen, type V, alpha 1 | 5.81 | included | 9.30E-12 |
| 2405001 | 2404999 | MARCKSL1 | MARCKS-like 1 | 5.74 | included | 1.10E-11 |
| 2535912 | 2535859 | CAPN10 | Calpain 10 | 5.62 | included | 8.34E-07 |