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. 2017 Jun 7;7:2956. doi: 10.1038/s41598-017-03429-x

Table 1.

Genotypes and minor allele frequencies of genes encoding toll-like receptors 3, 4, 7, 8, 9, and 10 in 135 children hospitalised for bronchiolitis and in the Finnish population.

SNP (Major > Minor) Major/Major Major/Minor Minor/Minor MAF FIN
TLR3 rs3775291 (C > T) 0.46 0.41 0.13 0.33 0.33
TLR4 rs4986790 (A > G) 0.84 0.16 0 0.08 0.12
TLR7 rs179008 (A > T) 0.61 (girls) 0.35 (girls) 0.04 (girls) 0.22 (girls and boys) 0.31 (girls and boys)
0.79 (boys) 0 0.21 (boys)
TLR8 rs2407992 (G > C) 0.35 (girls) 0.48 (girls) 0.17 (girls) 0.45 (girls and boys) 0.36 (girls and boys)
0.79 (boys) 0 0.49 (boys)
TLR9 rs187084 (T > C) 0.32 0.43 0.25 0.46 0.45
TLR10 rs4129009 (A > G) 0.84 0.15 0.01 0.08 0.08

MAF = minor allele frequency, FIN = Finnish MAFs as in ref. 20. N = 135 for TLR3, TLR4, TLR7, and TLR8; N = 134 for TLR9 and TLR10.