Table 2.
Associations Between Cord Blood Leptin Levels, Maternal BMI, and Neonatal Adiposity
Univariate | Multivariate* | |||||
---|---|---|---|---|---|---|
β value (95%CI) | r | p** | β value (95% CI) | r *** | p** | |
Exposure | Percent change in leptin per unit increase in maternal BMI | |||||
Maternal BMI | 2.2 (0.0 – 4.4) |
0.18 | 0.054 | 1.8 (−0.5 – 4.1) |
0.14 | 0.129 |
Outcomes | Change in outcome per 10% increase in leptin | |||||
Birth Weight (kg) | 0.024 (0.012 – 0.036) |
0.35 | <0.001 | 0.027 (0.017 – 0.037) |
0.45 | <0.001 |
Fat Mass (kg) | 0.011 (0.007 – 0.014) |
0.48 | <0.001 | 0.010 (0.007 – 0.014) |
0.47 | <0.001 |
% Body Fat | 0.235 (0.150 – 0.320) |
0.47 | <0.001 | 0.218 (0.135 – 0.300) |
0.44 | <0.001 |
Analyses were adjusted for maternal age at delivery, maternal race, gestational age in days, and neonatal sex
p values were calculated from linear regression models
Semi-partial correlation between exposure and outcome after controlling the latter for the adjusting covariates