Table 3.
Analysis of correlation between autonomic functions and group differences in CBF value after controlling for age, gender, and BMI.
| Autonomic functions (OFF state) | Anatomic location | r | P | ||
|---|---|---|---|---|---|
| OFF | HR-DB | R | Medial frontal gyrus | 0.358 | 0.008 |
| BRS | R | Middle frontal gyrus | 0.466 | 0.000 | |
| R | Medial frontal gyrus | 0.565 | 0.000 | ||
| L | Superior frontal gyrus | 0.520 | 0.000 | ||
| SP difference in the tilting test | R | Medial frontal gyrus | –0.396 | 0.006 | |
| L | Superior frontal gyrus | –0.472 | 0.001 | ||
| DP difference in the tilting test | L | Superior frontal gyrus | –0.402 | 0.006 | |
| ON | HR-DB | R | Inferior frontal gyrus | 0.458 | 0.001 |
| BRS | R | Inferior frontal gyrus | 0.448 | 0.001 | |
| L | Insula | 0.499 | 0.000 | ||
| R | Superior frontal gyrus | 0.457 | 0.001 | ||
| OFF-ON | BRS | L | Middle frontal gyrus | –0.679 | 0.008 |
BMI, body mass index; BRS, baroreflex sensitivity; CBF, cerebral blood flow; DP, diastolic pressure; HR_DB, heart rate response to deep breathing; L, left; NC, normal control; R, right; SP, systolic pressure; UPDRS, Unified Parkinson’s Disease Rating Scale.