Table 2.
Analysis of MyBP-C haploinsufficiency in HCM cat heart muscle.
Sample | Mean cMyBP-C relative to non-HCM | Percentage deficiency of MyBP-C | Significance (p) | Repeats (n) |
---|---|---|---|---|
H6 | 0.79 | 21 | <0.05 | 12 |
H7 | 0.70 | 30 | <0.001 | 6 |
H8 | 0.78 | 22 | <0.05 | 6 |
H10 | 0.78 | 22 | <0.05 | 6 |
H14 | 0.56 | 44 | <0.05 | 6 |
H16 | 0.81 | 19 | <0.001 | 6 |
Non-HCM and HCM cat samples were compared by one-way ANOVA and 5 samples showed significant haploinsuffficiency. * p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001. H16 is close to significance in the ANOVA test and is significant in a paired t-test when compared with non-HCM samples in the same gel.