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. 2017 Jun 8;10:183. doi: 10.3389/fnmol.2017.00183

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Copyright © 2017 Li, Wang, Li and Yuan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Vascular endothelial growth factor expression in NSCs is elevated via hypoxia-repressed miR-590. (A,B) Expressions of VEGF mRNA (A) and protein (B) were analyzed in NSCs expressing control or miR-590, under normoxia or hypoxia conditions, respectively. Data were presented as mean ± SD from at least three independent experiments. ^∗∗p < 0.01, vs. normoxia+control and hypoxia+miR-590; ns not significant, vs. normoxia+control. (C,D) Expressions of VEGF mRNA (C) and protein (D) were analyzed in PBS or FA-treated NSCs expressing control or miR-590, respectively. Data were presented as mean ± SD from at least three independent experiments. ^∗p < 0.05, vs. PBS+control and FA+miR-590; ns not significant, vs. PBS+control.