Fig. 4.

EGF did not modulate food intake or anxiety like behavior. A. Body weight decreased at 5 weeks, but remained constant until 10 weeks with EGF treatment. B. EGF treatment had no effect on food intake (over 24 h at the end point or C. performance in the light-dark box test. D. EGF-treated mice had higher plasma and E. brain levels of EGF, measured by ELISA. n = 7 per group. Data expressed as mean +/− S.E.M. *p < 0.05 by 2-way ANOVA and Sidak’s post-hoc analysis (A). *p < 0.05 by Students t-test (B-D).