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Peripheral EGF administration prevents cerebrovascular dysfunction in E4FAD-F mice. Fibrinogen levels are lower in the cortex (CX) of EGF-treated E4FAD-F mice (A.) and laminin coverage is higher in the CX and deep layer CX of EGF-treated E4FAD-F mice (B.) when compared to vehicle control treated mice. n = 7 per group. Data expressed as mean +/− S.E.M.*p < 0.05 by Students t test.
