Table 3.
Main and interaction effects of amyloid and CBF on recognition memory.
| Hippocampal CBF | Posterior Cingulate CBF | Precuneus CBF | Postcentral CBF | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Block | Variable | Block F | Block ΔR2 | B (SE) | β | t | Block F | Block ΔR2 | B (SE) | β | t | Block F | Block ΔR2 | B (SE) | β | t | Block F | Block ΔR2 | B (SE) | β | t |
| 1 | Age | 3.12 | 0.14 | -0.03 (0.02) | -0.23 | -1.73 | 3.12 | 0.14 | -0.03 (0.02) | -0.23 | -1.73 | 3.12 | 0.14 | -0.03 (0.02) | -0.23 | -1.73 | 3.12 | 0.14 | -0.03 (0.02) | -0.23 | -1.73 |
| Education | 0.08 (0.05) | 0.23 | 1.72 | 0.08 (0.05) | 0.23 | 1.72 | 0.08 (0.05) | 0.23 | 1.72 | 0.08 (0.05) | 0.23 | 1.72 | |||||||||
| Sex | 0.12 (0.26) | 0.06 | 0.48 | 0.12 (0.26) | 0.06 | 0.48 | 0.12 (0.26) | 0.06 | 0.48 | 0.12 (0.26) | 0.06 | 0.48 | |||||||||
| 2 | Aβ (+ versus -) | 1.98 | 0.01 | 0.26 (0.33) | 0.11 | 0.79 | 2.00 | 0.01 | 0.27 (0.33) | 0.12 | 0.83 | 2.13 | 0.01 | 0.32 (0.33) | 0.14 | 0.96 | 2.09 | 0.01 | 0.28 (0.33) | 0.12 | 0.86 |
| CBF | -0.004 (0.02) | -0.04 | -0.28 | 0.004 (0.01) | 0.05 | 0.39 | 0.01 (0.01) | 0.11 | 0.85 | 0.01 (0.02) | 0.10 | 0.75 | |||||||||
| 3 | Aβ × CBF | 3.97 | 0.15 | -0.13 (0.04)∗∗∗ | -0.43 | -3.46 | 3.17 | 0.11 | -0.07 (0.02)∗∗ | -0.37 | -2.80 | 3.00 | 0.12 | -0.07 (0.03)∗ | -0.34 | -2.52 | 2.36 | 0.06 | -0.06 (0.06) | -0.29 | -1.81 |
∗p < 0.05, ∗∗p ≤ 0.01, ∗∗∗p ≤ 0.001.
Dependent variable in all models is recognition corrected for false positive errors (i.e., Rey Auditory Verbal Learning recognition total hits–false positives).
B, unstandardized coefficient estimate.
SE, standard error.