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SM rate in the different treatment groups
| Groups | SM No | SM Yes | FU (years) median | ET (years) median |
|---|---|---|---|---|
| No therapy | 209 (95%) | 11 (5%) | 5 (0.1–23) | NA |
| HU | 599 (93%) | 42 (7%) | 6 (0.1–32) | 4 (0.1–30) |
| ALK | 24 (92%) | 2 (8%) | 12 (1–30) | 8 (0.4–23) |
| ALK + HU | 79 (92%) | 7 (8%) | 10 (2–26) | 9 (0.6–24) |
| ANA/IFN | 51 (96%) | 2 (4%) | 8 (2–21) | 4 (0.1–20) |
HU, hydroxyurea; ALK, alkylating agents; ANA, anagrelide; IFN, α‐interferon; SM, secondary malignancy; FU, follow‐up; ET, exposure time.
