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Treatment with Tolcapone significantly reduced tumor volume compared to control in vivo. Mice were injected with 2 million SMS‐KCNR NB cells and treated orally with 125 mg/kg Tolcapone every 24 h. A) Mean tumor volume of both treatment groups over time (one replicate shown, P < 0.05). B) Growth pattern of mouse tumors over time with each line representing a specific mouse in the experiment (one replicate shown, P < 0.05).
