Table 2.
Characteristics of CRC patients aged ≥50 years in relation to MSI
| MSI‐H | MSS | P | |
|---|---|---|---|
| n = 121 (%) | n = 2098 (%) | ||
| Gender | |||
| Female | 70 (7.7) | 841 (92.3) | <0.001 |
| Male | 51 (3.9) | 1257 (96.1) | |
| Age at diagnosis of CRC | |||
| Mean ± SD | 68.1 ± 9.56 | 66.4 ± 8.44 | 0.07 |
| Location | |||
| Proximal | 86 (12.9) | 582 (87.1) | <0.001 |
| Distal | 35 (2.3) | 1516 (97.7) | |
| Tumor size | |||
| Mean ± SD(mm) | 58.3 ± 35.9 | 44.6 ± 22.5 | <0.001 |
| TNM stage | |||
| 0‐I | 28 (5.6) | 471 (94.4) | <0.001 |
| 62 (8.8) | 642 (91.2) | ||
| 21 (3.2) | 635 (96.8) | ||
| 10 (2.8) | 350 (97.2) | ||
| Mucinous component | |||
| − | 79 (4.1) | 1868 (95.9) | <0.001 |
| + | 42 (15.4) | 230 (84.6) | |
| KRAS | |||
| Wild | 82 (6.5) | 1183 (93.5) | 0.01 |
| Mutant | 39 (4.1) | 915 (95.9) | |
| BRAF | |||
| Wild | 75 (3.5) | 2046 (96.5) | <0.001 |
| Mutant | 46 (46.9) | 52 (53.1) | |
Proximal, cecum to transverse colon; Distal, splenic flexure to rectum; TNM, tumor node metastasis; MSI‐H, high‐frequency microsatellite instability; MSS, microsatellite stable.