Table 2.
P-selectin (median fluorescence) in response to arachidonic acid (AA, aspirin test) and adenosine diphosphate (ADP, clopidogrel test) by antiplatelet medication taken prior to randomisation, for aspirin versus no aspirin and clopidogrel versus no clopidogrel. Data are number (%) or mean (standard deviation, SD) with 95% confidence intervals. Comparisons by Chi-square test or one-way analysis of variance.
| No aspirin | Aspirin | Difference | 2p | No clopidogrel | Clopidogrel | Difference | 2p | |
|---|---|---|---|---|---|---|---|---|
| AA | ||||||||
| Number (%) | 162 (24.1) | 494 (20.4) | 559 (20.2) | 97 (29.5) | ||||
| Mean (SD) | 570 (435) | 210 (188) | 360.3 (312.2, 408.4) | <0.001 | 261 (280) | 515 (389) | −254.1 (−318.6, − 189.6) | <0.001 |
| <400 (%) | 83 (51.2) | 463 (93.7) | −42.5 (−50.5, − 34.5) | <0.001 | 495 (88.6) | 51 (52.6) | 36 (25.7, 46.3) | <0.001 |
| <500 (%) | 86 (53.1) | 471 (95.3) | −42.3 (−50.2, − 34.4) | <0.001 | 503 (90) | 54 (55.7) | 34.3 (24.1, 44.5) | <0.001 |
|
| ||||||||
| ADP | ||||||||
| Number (%) | 165 (24.5) | 517 (21.3) | 585 (21.1) | 97 (29.5) | ||||
| Mean (SD) | 854 (361) | 947 (318) | −93.4 (−151.1, − 35.7) | 0.0015 | 969 (315) | 655 (296) | 314.5 (247.3,381.7) | <0.001 |
| <860 (%) [33] | 82 (49.7) | 211 (40.8) | 8.9 (0.2, 17.6) | 0.045 | 220 (37.6) | 73 (75.3) | −37.7 (−47.1, −28.2) | <0.001 |
| <625 (%) | 48 (29.1) | 77 (14.9) | 14.2 (6.6, 21.8) | <0.001 | 75 (12.8) | 50 (51.5) | −38.7 (−49, −28.4) | <0.001 |
| <500 (%) | 30 (18.2) | 38 (7.4) | 10.8 (4.5, 17.1) | <0.001 | 38 (6.5) | 30 (30.9) | −24.4 (−33.8, −15) | <0.001 |