Table 1.
Mean numbers of various chromosomal aberrations after damage induced by bleomycin (40 µg/mL) in the presence or absence of the decoction (100–600 µg/mL). DC, dicentric chromosome; AF, acentric fragments; ChB, chromatid breaks.
| Experimental groups | Concentration (μg/mL) |
DC per 100 spreads | DC% inhibition |
AF per 100 spreads |
AF% inhibition |
ChB per 100 spreads |
ChB% inhibition |
|---|---|---|---|---|---|---|---|
| Negative control | 0.037 ± 0.01 | 0.043 ± 0.01 | 0.063 ± 0.01 | ||||
|
| |||||||
| Decoction control | Dec. 100 300 600 |
0.027 ± 0.01 0.026 ± 0.01 0.029 ± 0.02 |
0.057 ± 0.01 0.049 ± 0.02 0.054 ± 0.01 |
0.043 ± 0.02 0.041 ± 0.01 0.047 ± 0.02 |
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|
| |||||||
| Bleomycin control | BLM 40 | 0.27 ± 0.04 | 0.36 ± 0.02 | 0.46 ± 0.04 | |||
|
| |||||||
| Test (decoction + bleomycin) | BLM 40 Dec. 100 300 600 |
0.17 ± 0.04 0.14 ± 0.03 0.16 ± 0.01 |
37.03 48.15 40.74 |
0.23 ± 0.02 0.19 ± 0.01 0.21 ± 0.02 |
36.11 47.23 41.67 |
0.34 ± 0.03 0.29 ± 0.02 0.33 ± 0.01 |
26.1 36.96 28.26 |