Effects of FMF on hepatic levels of MDA, GSH, GSH-Px, SOD, and CAT. Mice were intragastrically administered with either PBS or FMF at 100, 200, and 400 mg/kg body weight once daily for 7 consecutive days prior to single administration of APAP (500 mg/kg BW). Mice were killed at 12 h after APAP challenge. Liver samples were collected, and hepatic homogenates were used for the determination of (a) MDA, (b) GSH, (c) GSH-Px, (d) SOD, and (e) CAT levels by using the commercial kits. Results are shown as mean ± SD (n = 8 mice in each group). ∗∗∗p < 0.001 compared with the control group; ###p < 0.001, ##p < 0.01, #p < 0.05 compared with APAP-intoxicated group.