Table 2. Clinical and biochemical characteristics in type 2 diabetic subjects according to the quartiles of skin AF values.
Variables | Tertiles of skin AF values | P-value | ||
---|---|---|---|---|
Tertile 1 | Tertile 2 | Tertile 3 | ||
n | 120 | 120 | 122 | |
Age (years) | 50.2 ± 8.5 | 50.7 ± 7.9 | 50.5 ± 8.1 | 0.899 |
Sex (M/F) | 54/66 | 59/61 | 66/56 | 0.334 |
Duration of diabetes (years) | 10.3 ± 2.2 | 10.8 ± 2.4 | 10.5 ± 2.3 | 0.879 |
BMI (kg/m2) | 24.9 ± 3.2 | 25.3 ± 3.1 | 26.2 ± 2.8 | 0.123 |
SBP (mmHg) | 121.3 ± 7.8 | 123.1 ± 8.1 | 122.1 ± 8.2 | 0.135 |
DBP (mmHg) | 72.4 ± 5.9 | 73.1 ± 5.4 | 72.3 ± 5.9 | 0.154 |
HbA1c (%) | 7.1 ± 1.8 | 7.3 ± 1.5 | 8.7 ± 1.1 | 0.031 |
TC (mmol/l) | 5.47 ± 0.67 | 5.79 ± 0.69 | 6.12 ± 0.71 | <0.001 |
TG (mmol/l) | 1.68 ± 0.75 | 2.43 ± 0.79 | 3.15 ± 0.74 | <0.001 |
LDL-C (mmol/l) | 2.97 ± 0.61 | 3.58 ± 0.68 | 4.16 ± 0.59 | <0.001 |
HDL-C (mmol/l) | 1.12 ± 0.31 | 1.13 ± 0.35 | 1.09 ± 0.34 | 0.059 |
CRP (mg/l) | 1.76 ± 0.78 | 2.91 ± 0.77 | 4.12 ± 0.74 | <0.001 |
Fins (mU/l) | 13.7 ± 4.7 | 13.1 ± 4.9 | 13.5 ± 3.9 | 0.326 |
HOMA-IR | 4.46 ± 2.33 | 4.49 ± 2.38 | 4.50 ± 2.29 | 0.599 |
Irisin (ng/ml) | 23.59 ± 4.88 | 16.67 ± 5.23 | 8.46 ± 4.16 | <0.001 |
Skin AF (AU) | 2.06 (1.74 – 2.38) | 2.71 (2.41 – 3.01) | 3.39 (3.08 – 3.71) | <0.001 |
SBP, systolic blood pressure; DBP, diastolic blood pressure.