Table 1. Fitted Dielectric Parameters to DEP Spectraa.
parameter (unit) | shScramble (HEK) (Ct = 25%) | shDRP (HEK) (Ct = 95%) | Mfn-KO (MEF) (Ct = 17%) | DRP-KO (MEF) (Ct = 91%) |
---|---|---|---|---|
εmem | 14 | 14 | 13 | 13 |
σmem (S/m) | 0.1 × 10–6 | 0.1 × 10–6 | 0.1 × 10–5 | 0.1 × 10–5 |
εcytoplasm | 60 | 60 | 60 | 65 |
σcytoplasm (S/m) | 0.30 | 0.52 | 0.35 | 0.56 |
εnucEnvelope | 25 | 25 | 25 | 25 |
σnucEnvelope (S/m) | 0.9 × 10–3 | 3 × 10–3 | 1.3 × 10–3 | 3 × 10–3 |
εnucleus | 60 | 60 | 60 | 60 |
σnucleus (S/m) | 1.4 | 1.4 | 1.5 | 1.4 |
See Supporting Information section S6.