Table 1.

Overview of model parameters

Model parameters		Contribution	No. of parameters	Prior				Posterior
				Distribution	Mean	SD	Source	Median	CR
Study population	Age group size	Fixed	6 age groups	–	–	–	KHDSS [4]	–	–
	Contact patterns	Fixed	6 × 6 age groups	–	–	–	KHDSS [5]	–	–
	Carriage prevalence	Outcome	2 types × 6 age groups	–	–	–	KHDSS [11]	–	–
	IPD	Outcome	2 types × 6 age groups	–	–	–	KHDSS [12]	–	–
	Observed vaccine coverage	Fixed	27,040 (weekly age and time)	–	–	–	KHDSS [4]	–	–
Transmission dynamics	Clearance rates	Fixed	2 types × 4 age groups				KHDSS [15]
	VE carriage (toddlers)	Fitted - prior	1	Normal	0.36	0.15	KHDSS [11]	0.56	0.41–0.72
	VE IPD (infants)	Fitted - prior	1	Normal	0.80	0.1	[22]	0.86	0.67–0.99
	Duration of protection (toddlers)	Fitted - prior	1	Normal	6 years	3	[23, 24]	5.50	2.05–11.01
	Relative level of infant protection	Fitted - prior	1	Normal	1	0.1	Assumption	0.97	0.78–1.17
	Competition parameter	Fitted - prior	1	Log-normal	0.15	0.15	[17, 18]	0.19	0.07–0.44
	Susceptibility to infection	Fitted - no prior	2 types × 4 age groups
	Invasiveness	Fitted - no prior	2 types × 4 age groups

CR Credible range, VE Vaccine efficacy