Table 2.
Factors Affecting HPV Knowledge and Willingness for HPV Vaccination among the General Female Population
| HPV knowledge score ≥ 4, N (%) | HPV knowledge score < 4, N (%) | OR* (95% CI) | Willing to be vaccinated, N (%) | Not willing to be vaccinated, N (%) | OR* (95% CI) | |
|---|---|---|---|---|---|---|
| aAge | 2686 (23.0) | 8995 (77.0) | 1.12 (1.07–1.18) | 9019 (77.2) | 2662 (22.8) | 0.88 (0.84–0.93) |
| Marriage status | ||||||
| Not married | 774 (26.1) | 2187 (73.9) | 1 | 2190 (74.0) | 771 (26.0) | 1 |
| Married | 1912 (21.9) | 6808 (78.1) | 0.75 (0.63–0.91) | 6829 (78.3) | 1891 (21.7) | 1.21 (1.00–1.46) |
| Education | ||||||
| < Junior high school | 785 (13.1) | 5186 (86.9) | 1 | 4561 (76.4) | 1410 (23.6) | 1 |
| ≥ Senior high school | 1901 (33.3) | 3809 (66.7) | 1.84 (1.63–2.08) | 4458 (78.1) | 1252 (21.9) | 0.94 (0.83–1.06) |
| Occupation | ||||||
| Unemployed | 633 (29.0) | 1550 (71.0) | 1 | 1688 (77.3) | 495 (22.7) | 1 |
| Government/medical/clerking | 625 (41.7) | 875 (58.3) | 1.19 (1.02–1.38) | 1209 (80.6) | 291 (19.4) | 0.98 (0.82–1.17) |
| Farmers | 436 (10.5) | 3706 (89.5) | 0.51 (0.43–0.60) | 3168 (76.5) | 974 (23.5) | 1.27 (1.10–1.48) |
| Total family income | ||||||
| < 30,000 RMB/year | 1620 (19.8) | 6544 (80.2) | 1 | 4269 (74.5) | 1463 (25.5) | 1 |
| ≥ 30,000 RMB/year | 1066 (30.3) | 2451 (69.7) | 1.30 (1.16–1.45) | 4750 (79.8) | 1199 (20.2) | 1.30 (1.17–1.45) |
| Gynecological exam frequency | ||||||
| Infrequent (< annually) | 1620 (19.8) | 6544 (80.2) | 1 | 6161 (75.5) | 2003 (24.5) | 1 |
| Annually | 1066 (30.3) | 2451 (69.7) | 1.47 (1.33–1.63) | 2858 (81.3) | 659 (18.7) | 1.12 (1.01–1.25) |
| Genital infection history | ||||||
| No history | 1543 (20.1) | 6150 (79.9) | 1 | 5723 (74.4) | 1970 (25.6) | 1 |
| Positive history | 1143 (28.7) | 2845 (71.3) | 1.47 (1.32–1.63) | 3296 (82.6) | 692 (17.4) | 1.35 (1.21–1.50) |
| NIP vaccine knowledge | ||||||
| None | 120 (10.0) | 1082 (90.0) | 1 | 873 (72.6) | 329 (27.4) | 1 |
| Yes but not vaccinated | 719 (18.2) | 3233 (81.8) | 1.50 (1.19–1.90) | 2972 (75.2) | 980 (24.8) | 1.01 (0.86–1.20) |
| Yes and vaccinated | 1847 (28.3) | 4680 (71.7) | 1.54 (1.22–1.93) | 5174 (79.3) | 1353 (20.7) | 1.22 (1.03–1.45) |
| Non-NIP vaccine knowledge | ||||||
| None | 172 (8.9) | 1762 (91.1) | 1 | 1401 (72.4) | 533 (27.6) | 1 |
| Yes but not vaccinated | 1647 (23.0) | 5508 (77.0) | 1.64 (1.36–1.98) | 5503 (76.9) | 1652 (23.1) | 1.07 (0.93–1.23) |
| Yes and vaccinated | 867 (33.4) | 1725 (66.6) | 2.32 (1.89–2.85) | 2115 (81.6) | 477 (18.4) | 1.31 (1.11–1.56) |
| Cervical cancer anxiety | ||||||
| No | 609 (18.0) | 2770 (82.0) | 1 | 2204 (65.2) | 1175 (34.8) | 1 |
| Yes | 2077 (25.0) | 6225 (75.0) | 1.45 (1.30–1.62) | 6815 (82.1) | 1487 (17.9) | 2.23 (2.02–2.45) |
| HPV vaccine acceptance for herself | ||||||
| No | 318 (11.9) | 2344 (88.1) | 1 | ------------- | ------------- | ------------- |
| Yes | 2368 (26.3) | 6651 (73.7) | 2.26 (1.94–2.63) | ------------- | ------------- | ------------- |
| HPV knowledge score | ||||||
| <4 points on 1–8 scale | ------------- | -------------------------- | 6651 (73.9) | 2344 (26.1) | 1 | |
| ≥4 points on 1–8 scale | ------------- | -------------------------- | 2368 (88.2) | 318 (11.8) | 2.31 (2.02–2.64) | |
OR, Odds Ratio; CI, Confidence Interval;
a
Age of participants was subjected to an ordinal regression analysis with the following age groups: 15–19 years, 20–29 years, 30–39 years, 40–49 years, and 50–59 years;
*
Variables in Table 2, besides sexual active status, were included in the multivariate logistic regression analyses. The acceptance of the vaccine for a daughter was also included in the model of HPV knowledge. Sexual active status and the acceptance of the vaccine for a daughter were not statistically significant