Table 1.

Significantly deregulated genes associated with glycolysis (GO:0006096) based on CCRT response in rectal cancer

Probe	Comparison log2 ratio	Comparison P-value	Gene Symbol	Gene Name	Biological Process	Molecular Function
217238_s_at	1.1475	0.0002	ALDOB	aldolase B; fructose-bisphosphate	fructose metabolic process, glycolysis, metabolic process	catalytic activity, fructose-bisphosphate aldolase activity, lyase activity
204705_x_at	1.1092	<0.0001	ALDOB	aldolase B; fructose-bisphosphate	fructose metabolic process, glycolysis, metabolic process	catalytic activity, fructose-bisphosphate aldolase activity, lyase activity
211357_s_at	0.9714	0.0004	ALDOB	aldolase B; fructose-bisphosphate	fructose metabolic process, glycolysis, metabolic process	catalytic activity, fructose-bisphosphate aldolase activity, lyase activity
204704_s_at	0.3209	0.0098	ALDOB	aldolase B; fructose-bisphosphate	fructose metabolic process, glycolysis, metabolic process	catalytic activity, fructose-bisphosphate aldolase activity, lyase activity
1558365_at	-0.4005	0.0049	PGK1	phosphoglycerate kinase 1	glycolysis, phosphorylation	ATP binding, kinase activity, nucleotide binding, phosphoglycerate kinase activity, transferase activity
213564_x_at	-0.3606	0.0045	LDHB	lactate dehydrogenase B	anaerobic glycolysis, anti-apoptosis, apoptosis, cellular carbohydrate metabolic process, glycolysis, protein folding, tricarboxylic acid cycle intermediate metabolic process	Hsp70/Hsc70 protein regulator activity, L-lactate dehydrogenase activity, oxidoreductase activity, oxidoreductase activity; acting on the CH-OH group of donors; NAD or NADP as acceptor, protein binding