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Comparison to prior studies investigating use of TMZ in LGG
| Study | # Patients | Median F/U | Response Rate (CR + PR) | 3y PFS | 3y OS |
|---|---|---|---|---|---|
| Brada et al14 | 30 | 3 y | 10% | 66% | 82% |
| Quinn et al17 | 46 | <1 y | 61% | NR | NR |
| Hoang-Xuan et al16 | 60 | 1.2 y | 17% | NR | NR |
| Kesari et al15 | 44 | 3 y | 20% | 57% | 81% |
| UCSF TMZ | 120 | 7.5 y | 6% | 58% | 81% |
F/U, follow-up; CR, complete response; PR, partial response. NR, not reported; UCSF, University of California, San Francisco.
