Table 4.
Comparison to recent cooperative group studies utilizing adjuvant radiation
| RTOG 9802 RT7 | RTOG 9802 RT+PCV7 | RTOG 0424 RT+TMZ23 |
UCSF TMZ |
|
|---|---|---|---|---|
| Median age, y | 40 | 41 | 49 | 39 |
| Histology | ||||
| Oligodendroglioma | 45% | 40% | 23% | 48% |
| Oligoastrocytoma | 31% | 31% | 22% | 17% |
| Astrocytoma | 23% | 29% | 55% | 36% |
| Extent of resection | ||||
| GTR | 9% | 11% | 19% | 0% |
| STR | 45% | 41% | 61% | 77% |
| Biopsy only | 47% | 48% | 16% | 23% |
| Median PFS (y) | 4.0 | 10.4 | 4.5 | 3.8 |
| Median OS (y) | 7.8 | 13.3 | NR (>5 y) | 9.7 |
RT, radiotherapy; UCSF, University of California, San Francisco; GTR, gross total resection; STR, subtotal resection; NR, not reached.