Table 2.
Multivariate proportional subdistribution hazard models for the competing risks of neurologic and nonneurologic death.
| Neurologic death | |||
|---|---|---|---|
| HR | CI | P value | |
| DS-GPA ≤ 2 | 1.54 | 1.14–2.08 | .005 |
| Lowest SRS dose (continuous) | 0.93 | 0.89–0.98 | .004 |
| Melanoma histology | 1.63 | 1.13–2.34 | .009 |
| Number of brain metastases (continuous) | 1.10 | 1.05–1.16 | <.001 |
| Nonneurologic death | |||
| HR | CI | P value | |
| Age (continuous) | 1.01 | 1.00–1.02 | .03 |
| Nonmelanoma histology | 2.00 | 1.38–2.91 | <.001 |
| Presence of extracranial disease | 1.86 | 1.30–2.66 | <.001 |
| Progressive systemic disease | 1.47 | 1.13–1.90 | .004 |
Abbreviations: CI, 95% confidence interval; DS-GPA, diagnosis-specific graded prognostic assessment, HR, hazard ratio; SRS, stereotactic radiosurgery.