Fig. 3.

Binding site residues and the corresponding change in affinity when they are mutated. All positions in this figure are shown as cysteine and are colour coded according to the extent of the change in affinity this mutation caused. Residues that are thought to have a structural role have been omitted. The structure is Model-1, and more details of the effects of these cysteine substitutions can be found in Table 2, Table 3.