Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
EP4 antagonists block PGE2 Binding to EP4. HEK293/EP4 membrane preparations were treated with a constant concentration (0.3 nmol/L) of [3H]‐PGE2 and various concentrations of indicated compounds for 90 min at room temperature. The results are expressed as % antagonism with membrane preparations that contained no antagonists serving as control (100%). The figure is a representative of results from experiments of n = 10 for compound‐1, n = 12 for compound‐2 and n = 8 for CJ‐023,423.
