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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Immunol Res. 2017 Jun;65(3):739–749. doi: 10.1007/s12026-017-8913-3

Figure 2. Blockade of Notch signaling pathway augments macrophage/neutrophil trafficking in APAP-induced liver injury.

Figure 2

(A) Liver macrophages were detected by immunohistochemical staining using mAb against mouse CD68+ in APAP-challenged livers after DAPT or DMSO treatment. (B) Quantification of CD68+ macrophages per high power field. Results scored semi-quantitatively by averaging the number of positively-stained cells (mean±SD)/field at 200× magnification. Representative of 4–6 mice/group. **p<0.01. (C) Liver neutrophil accumulation, analyzed by MPO activity (U/g). Mean±SD (n=4–6 samples/group). *p<0.05.