Table 3.
HPV Status and Molecular Features of p16INK4a in HNSCC Subset Samples (n=53)
HPV infection | Total | P | OR | 95% CI | ||
---|---|---|---|---|---|---|
Positive | Negative | |||||
Positive p16INK4a expression (n=19) | ||||||
p16INK4a (M) | 2 (5.1) | 6 (15.4) | 8 (20.5) | 0.53 | 1.52 | 0.47-4.89 |
p16INK4a (U) | 2 (14.3) | 9 (64.3) | 11 (79.5) | |||
Negative p16INK4a expression (n=34) | ||||||
p16INK4a (M) | 18 (52.9) | 13 (38.2) | 31 (91.2) | <0.001 | 26.4 | 1.49-467.8 |
p16INK4a (U) | 0 (0) | 3 (8.8) | 3 (8.8) | |||
Total | 22 (41.5) | 31 (58.5) | 53 (100) |
M, methylated; U, unmethylated