Table 3.
Relationship between Clinicopathological Parameters and Immunohistochemical Expression of Hsp27 and Hsp70 in the Esophageal Squamous Cell Carcinoma
| Hsp27 | Hsp70 | |||||
|---|---|---|---|---|---|---|
| Neg n (%) | Pos n (%) | p | Neg n (%) | Pos n (%) | p | |
| Gender (n=28) | NS | NS | ||||
| Male | 3 (10.71) | 20 (71.43) | 1 (3.57) | 22 (78.57) | ||
| Female | 2 (7.14) | 3 (10.72) | 1 (3.57) | 4 (14.29) | ||
| Age (n=28) | NS | NS | ||||
| ≥60 | 2 (7.14) | 10 (35.73) | 0 (0.00) | 12 (42.86) | ||
| <60 | 3 (10.71) | 13 (46.42) | 2 (7.14) | 14 (50.00) | ||
| Surgicalmargin (n=28) | NS | NS | ||||
| compromised | 0 (0.00) | 9 (32.10) | 1 (3.57) | 8 (28.6) | ||
| notcompromised | 5 (17.9) | 14 (50.00) | 1 (3.57) | 18 (64.30) | ||
| Lymph node status (n=20) | NS | NS | ||||
| Positive | 0 (0.00) | 7 (35.00) | 1 (5.00) | 6 (30.00) | ||
| Negative | 4 (20.00) | 9 (45.00) | 1 (5.00) | 12 (60.00) | ||
| Tumor differentiation(n=28) | NS | NS | ||||
| well-differentiated | 2 (7.14) | 2 (7.14) | 1 (3.57) | 3 (10.72) | ||
| moderatelydifferentiated | 2 (7.14) | 17 (60.71) | 2 (7.14) | 17 (60.71) | ||
| undifferentiated | 1 (3.57) | 4 (14.29) | 0 (0.00) | 5 (17.86) | ||
| Follow-up (n=28) | ||||||
| Live without disease | 5 (21.74) | 4 (17.39) | <0.05a | 3 (10.71) | 6 (21.42) | <0.05b |
| Live with disease | 2 (7.14) | 1 (3.57) | 3 (10.71) | 0 (0.00) | ||
| Death bycancer | 8 (34.78) | 6 (26.09) | 5 (17.85) | 9 (32.14) | ||
| Lost | 2 (7.14) | 0 (0.00) | 2 (7.14) | 0 (0.00) |
a
, Hsp27 expression exhibited a significantly better prognosis;
b
, Hsp70 expression exhibited a significantly better prognosis; NS, not significant