Table 1.
Characteristics | Responders | Non-responders | P-value | |
---|---|---|---|---|
(PR) | (SD+PD) | (Fisher’s exact test) | ||
N=26 | n= 2 | n= 24 | ||
Gender | ||||
Male | 9 (34.6) | 1 (11.1) | 8 (88.9) | 1.000 |
Female | 17 (65.4) | 1 (5.9) | 16 (94.1) | |
Age (year) | ||||
Median (range) | 61.5 (44-89) | |||
< 65 Year | 14 (53.8) | 0 (0.0) | 14 (100.0) | 0.203 |
≥ 65 Year | 12 (46.2) | 2 (16.7) | 10 (83.3) | |
Extent of disease | ||||
Locally advanced | 7 (26.9) | 0 (0.0) | 7 (100.0) | 0.395* |
Metastatic | 14 (53.8) | 2 (14.3) | 12 (85.7) | |
Mixed | 5 (19.2) | 0 (0.0) | 5 (100.0) | |
Primary tumor site | ||||
Cholangiocarcinoma | 22 (84.6) | 2 (9.1) | 20 (90.9) | 1.000 |
Gallbladder | 4 (15.4) | 0 (0.0) | 4 (100.0) | |
Performance status(ECOG) | ||||
0 | 4 (15.4) | 0 (0.0) | 4 (100.0) | 0.773* |
1 | 21 (80.8) | 2 (9.5) | 19 (90.5) | |
2 | 1 (3.8) | 0 (0.0) | 1 (100.0) | |
Chemotherapeutic Regimens | ||||
Gemcitabine/Cisplatin | 20 (76.9) | 1 (5.0) | 19 (95.0) | 0.415 |
Gemcitabine/Carboplatin | 6 (23.1) | 1 (16.7) | 5 (83.3) |
-Chi-square test