Skip to main content
. 2017 Jun 5;13:1744806917711612. doi: 10.1177/1744806917711612

Figure 4.

Figure 4.

MiR-9 regulates axon regeneration by targeting FoxP1 expression. (a) Representative Western blot images of FoxP1 in cultured adult mouse sensory neurons with miR-9 mimics and/or FoxP1 plasmid. Note that expression of miR-9 leads to markedly decreased level of FoxP1, which can be fully reversed by expression of FoxP1. (b) Quantification of FoxP1 level from three independent experiments (normalized to actin, n = 3). Error bars represent SEM. **P < 0.01 indicates significant difference from Control; ##P < 0.01 indicates significant difference from miR-9-treated condition. (c) Representative images of cultured adult sensory neurons with EGFP, EGFP + miR-9, FoxP1, and FoxP1 + miR-9. Scale bar = 100 µm. (d) Quantification of the average length of the longest axons (normalized to the average length of the control axons, n = 3). Error bars represent SEM. **P < 0.01 indicates significant difference from Control; ##P < 0.01 indicates significant difference from miR-9-treated condition.