Table 2. Comparison of demographic and clinical features between groups.
| 21 GRN+/A152T+ | 14 GRN+/A152T- | p | |
|---|---|---|---|
| Sex (female %) | 71.4% | 50% | 0.29 |
| Age of onset (years) | 61.0 ± 7.1 | 61.4 ± 9.2 | 0.62 |
| Initial diagnosis | bvFTD (10) | bvFTD (9) | 0.98 |
| nfvPPA (5) | nfvPPA (2) | ||
| AD (3) | AD (2) | ||
| CBS (1) | CBS (0) | ||
| Dementia NOS (2) | PD (1) | ||
| Time to onset of motor symptoms (years) | 3.1 ± 1.3 | 3.1 ± 1.7 | 0.84 |
| % developing CBS throughout the disease course | 57.1% | 35.7% | 0.31 |
| % with asymmetry on structural MRI | 54.5% | 70% | 0.66 |
AD: Alzheimer’s disease; bvFTD: behavioral variant frontotemporal dementia; CBS: corticobasal syndrome; nfvPPA: nonfluent/agrammatic variant of primary progressive aphasia. NOS: not otherwise specified.