Table 3. Comparison of neuropsychological performance between groups.
8 GRN+/A152T+ | 9 GRN+/A152T- | p | |
---|---|---|---|
MMSE | 23.6 ± 4.4 | 24.5 ± 3.9 | 0.66 |
Digit span forward | 4.7 ± 0.7 | 4.6 ± 0.7 | 0.66 |
Digit span backward | 2.4 ± 1.3 | 3.1 ± 0.7 | 0.15 |
TMT-A | 100.8 ± 50.6 | 76.8 ± 26.3 | 0.34 |
TMT-B | 200 ± 36.7 | 180.2 ± 73.9 | 0.60 |
Semantic verbal fluency | 9.9 ± 4.0 | 11.3 ± 4.5 | 0.50 |
Phonetic verbal fluency | 3.7 ± 3.1 | 7.3 ± 6.2 | 0.23 |
Reasoning | 5.1 ± 3.5 | 4.3 ± 2.1 | 0.54 |
Verbal comprehension | 5.6 ± 0.7 | 5.9 ± 0.3 | 0.35 |
Repetition | 9.9 ± 0.3 | 9.9 ± 0.3 | 0.93 |
Unilateral praxis | 8.6 ± 3.2 | 9.8 ± 0.4 | 0.34 |
Bilateral praxis | 6.1 ± 2.3 | 6.4 ± 1.7 | 0.75 |
CERAD Word List 1 | 2.2 ± 1.4 | 2.7 ± 0.9 | 0.43 |
CERAD Word List 2 | 3.6 ± 1.5 | 4.1 ± 1.1 | 0.45 |
CERAD Word List 3 | 4.7 ± 2.0 | 5.2 ± 2.1 | 0.65 |
CERAD Word List Recall | 3.2 ± 1.5 | 2.4± 2.0 | 0.34 |
CERAD Word List Recognition | 17.5 ± 1.9 | 16.3 ± 3.6 | 0.38 |
CERAD Constructional Praxis | 9.1 ± 3.2 | 9.3 ± 1.8 | 0.89 |
MMSE score change at 1 year | -5.2 ± 3.8 | -3.7 ± 2.8 | 0.45 |
CERAD: Consortium to Establish a Registry for Alzheimer’s Disease; MMSE: Mini-Mental State Examination; TMT: Trail Making Test.