Table 1. Selected characteristics of the studied population of nurses and midwives in the cross-sectional study.
| Characteristic | n = 710 | BRCA1 | BRCA2b | ||
|---|---|---|---|---|---|
| Methylated n(%) n = 153 (21.5) | Unmethylated n(%) n = 557(78.5) | Methylated n(%) n = 130(18.3) | Unmethylated n(%) n = 579(81.5) | ||
| Age (years), AM (SD) | 49.3 (5.3) | 48.7 (5.3) | 49.4 (5.3) | 48.3 (5.3) | 49.4 (5.3) |
| Age β–coefficient, 95%CIc | 0.169(-0.058–0.010) | -0.039(-0.075–0.002) | |||
| System of work, n (%) | |||||
| Current rotating nights | 347 (48.9) | 78 (51.0) | 269 (48.3) | 66 (50.8) | 281 (48.5) |
| Current day work | 363 (51.1) | 75 (49.0) | 288 (51.7) | 64 (49.2) | 298 (51.5) |
| Duration of the night work in years, n (%) | |||||
| ≤10 | 189 (26.6) | 38 (24.8) | 151 (27.1) | 35 (26.9) | 153 (26.4) |
| >10-≤20 | 175 (24.7) | 41 (26.8) | 134 (24.1) | 31 (23.9) | 144 (24.9) |
| >20 | 346 (48.7) | 74 (48.4) | 272 (48.8) | 64 (49.2) | 282 (48.7) |
| Smoking, n (%) | |||||
| never | 302 (42.5) | 60 (39.2) | 242 (43.5) | 54 (41.5) | 248 (42.8) |
| past | 191 (26.9) | 35 (22.9) | 156 (28.0) | 35 (26.9) | 155 (26.8) |
| current | 217 (30.6) | 58 (37.9) | 159 (28.5) | 41 (31.5) | 176 (30.4) |
| Amount of smoked cigarettes per day among current smokers, n (%) | |||||
| 1–4 | 30 (13.8) | 8 (5.2) | 22 (4.0) | 6 (4.6) | 24 (4.2) |
| 5–14 | 98 (45.2) | 28 (18.3) | 70 (12.6) | 21 (16.2) | 77 (13.3) |
| ≥15 | 89 (41.0) | 22 (14.4) | 67 (12.0) | 14 (10.8) | 75 (13.0) |
| Smoking duration among ever smokers in yearsb, n (%) | |||||
| ≤22.6 | 119 (29.2) | 27 (29.0) | 92 (29.2) | 26 (34.2) | 93 (28.1) |
| >22.6-≤31.0 | 126 (31.0) | 24 (25.8) | 102 (32.4) | 19 (25.0) | 107 (32.3) |
| >31.0 | 162 (39.8) | 42 (45.2) | 120 (38.1) | 31 (40.8) | 130 (39.3) |
| Packyears, AM (SD) | 9.2 (10.9) | 10.3 (11.7) | 8.9 (10.7) | 9.2 (11.3) | 9.1 (10.8) |
| Alcohol drinking (no of drinks/week), AM (SD) | 0.6 (0.7) | 0.6 (0.6) | 0.6 (0.7) | 0.6 (0.9) | 0.6 (0.7) |
| Lifelong duration of alcohol drinking (years), AM (SD) | 29.9 (8.1) | 29.3 (8.2) | 30.1 (8.0) | 29.3 (7.8) | 30.0 (8.1) |
| Drinkyears, AM (SD) | 11.3 (14.9) | 10.6 (9.9) | 11.5 (16.0) | 12.8 (19.6) | 10.9 (13.7) |
| Current alcohol abstinenceb, n (%) | |||||
| yes | 35 (4.9) | 10 (6.5) | 25 (4.5) | 5 (3.9) | 30 (5.2) |
| no | 671 (94.5) | 142 (92.8) | 529 (95.0) | 124 (95.4) | 546 (94.3) |
| BMI (kg/m2), n (%) | |||||
| <25 | 262 (36.9) | 58 (37.9) | 204 (36.6) | 54 (41.5) | 208 (35.9) |
| ≥25 - <30 | 281 (39.6) | 58 (37.9) | 223 (40.0) | 50 (38.5) | 230 (39.7) |
| ≥30 | 167 (23.5) | 37 (24.2) | 130 (23.3) | 26 (20.0) | 141 (24.4) |
| WHRb, n (%) | |||||
| ≤0.85 | 529 (74.5) | 109 (71.2) | 420 (75.4) | 101 (77.7) | 427 (73.8) |
| >0.85 | 180 (25.4) | 44 (28.8) | 136 (24.4) | 29 (22.3) | 151 (26.1) |
| Total physical activity (MET*hrs/wk), AM (SD) | 221.2 (85.7) | 215.8 (80.4) | 222.7 (87.2) | 221.3 (78.7) | 221.2 (87.3) |
| Recreational PAb, n (%) | |||||
| None | 198 (27.9) | 36 (23.5) | 162 (29.1) | 38 (29.2) | 160 (27.6) |
| Any | 510 (71.8) | 117 (76.5) | 393 (70.6) | 92 (70.8) | 417 (72.0) |
| Total folate intake per day in μg AM (SD) | 382 (138.5) | 384.6 (139.0) | 381.3 (138.5) | 384.1 (137.5) | 381.3 (138.9) |
| Total folate intake–β coefficient per 100 μg, 95%CIc | 0.027(-0.099–0.154) | 0.085(-0.0458–0.216) | |||
a—abbreviations: BMI—Body Mass Index; WHR–Waist to Hip Ratio; MET—Metabolic Equivalent
b—missing data for alcohol abstinence for 4 women; WHR, and WHtR for 1 woman, for recreational activity for 2 women, for methylation index in BRCA2 for 1 woman, smoking duration for 1 women
c–derived from univariate logistic regression