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. Author manuscript; available in PMC: 2017 Oct 15.
Published in final edited form as: Bioorg Med Chem Lett. 2016 Sep 13;26(20):4884–4887. doi: 10.1016/j.bmcl.2016.09.030

Figure 4.

Figure 4

a) Western blot analysis of PUMA in H1299 cells treated with DMSO, monomer 2 (20 μM) or dimer 1 (3, 5 and 10 μM) for 24 hrs. b) RNA was harvested 8 and 24 hrs, respectively, after treatment with DMSO, monomer 2 (20 μM), or dimer 1 (3 and 10 μM). PUMA expression was analyzed by qRT-PCR. Expression was normalized to 18S levels and is reported as x-fold increase over untreated control.