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Protein levels of ERK a., p-ERK b., PKA c., p-PKA d., p-CREB f., and BDNF g. signifcantly decreased in the hippocampus (p < 0.05) to 91.6%, 71.1%, 74.5%, 92.5%, 67.4%, and 64.2%, of their initial values, while the CREB e. protein level signifcantly increased to 129%.
