Table 2. Correlation of Notch receptor mRNA high expression with PFS in pathological grades of ovarian cancer patients.
Notch receptors | Pathological grades | Cases | HR 95% CI | P value |
---|---|---|---|---|
Notch 1 | I | 37 | 0.68 (0.23–2.03) | 0.48 |
II | 247 | 1.19 (0.89–1.61) | 0.25 | |
III | 790 | 0.93 (0.78–1.11) | 0.44 | |
Notch 2 | I | 37 | 0.93 (0.31–2.77) | 0.89 |
II | 247 | 1.45 (1.07–1.96) | 0.016 | |
III | 790 | 1.03 (0.87–1.23) | 0.71 | |
Notch 3 | I | 37 | 1.66 (0.54–5.08) | 0.37 |
II | 247 | 1.21 (0.89–1.63) | 0.22 | |
III | 790 | 0.94 (0.79–1.12) | 0.48 | |
Notch 4 | I | 37 | 0.38 (0.12 −1.22) | 0.091 |
II | 247 | 1.03 (0.76–1.38) | 0.86 | |
III | 790 | 1.04 (0.88–1.24) | 0.64 |
Note: three-tier grading scheme for pathological classification.