Table 1. Correlation between SerpinB2 overexpression and BC clinical parameters.
| Parameters | No. of cases | SerpinB2-high (%) | SerpinB2-low (%) | P-value |
|---|---|---|---|---|
| Breast cancer | 337 | 216(64.1) | 121(35.9) | |
| Age | ||||
| ≧50 | 235 | 156(66.4) | 79(33.6) | 0.184 |
| <50 | 102 | 60(58.8) | 42(41.2) | |
| Tumor size | ||||
| ≧2cm | 237 | 164(69.2) | 73(30.8) | 0.002 |
| <2cm | 100 | 52(52.0) | 48(48.0) | |
| TNM stage | ||||
| I-II | 229 | 133(58.1) | 96(41.9) | 0.000 |
| III-IV | 108 | 83(76.9) | 25(23.1) | |
| Histology grade | ||||
| Well | 59 | 34(57.6) | 25(42.4) | 0.129 |
| Moderate | 206 | 129(62.6) | 77(37.4) | |
| Poor | 72 | 53(73.6) | 19(26.4) | |
| LN metastasis | ||||
| Negative | 189 | 105(55.6) | 84(44.4) | 0.000 |
| Positive | 148 | 111(75.0) | 37(25.0) | |
| ER | ||||
| Negative | 144 | 97(67.4) | 47(32.6) | 0.2803 |
| Positive | 193 | 119(61.7) | 74(38.3) | |
| PR | ||||
| Negative | 170 | 111(65.3) | 59(34.7) | 0.643 |
| Positive | 167 | 105(62.9) | 62(37.1) | |
| HER2 | ||||
| Negative | 192 | 125(65.1) | 67(34.9) | 0.657 |
| Positive | 145 | 91(62.8) | 54(37.2) |
ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal receptor 2.