Table 1. In vitro cytotoxic activity represented as IC50 values (μM) on A549, HeLa and 786-O cell lines of seven compounds isolated from Calotropis gigantea were measured by MTT assays.
Compounds | IC50 (μM, A549) | IC50 (μM, HeLa) | IC50 (μM, 786-O) |
---|---|---|---|
1 | 16.5 ± 2.9 | 13.3 ± 2.2 | 20.0 ±1.4 |
2 | 12.0 ± 0.6 | 5.2 ± 1.4 | 14.2 ± 0.8 |
5 | > 25 | > 25 | > 25 |
6 | 4.6 ± 1.2 | 4.3 ± 0.9 | 5.3 ± 1.6 |
8 | 4.2 ± 0.7 | 3.7 ± 1.0 | 6.0 ± 2.1 |
9 | 2.2 ± 1.2 | 1.2 ± 0.2 | 3.2 ± 0.7 |
10 | > 25 | > 25 | > 25 |