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. 2017 Mar 25;8(20):33144–33158. doi: 10.18632/oncotarget.16562

Figure 1. Roles of linc-ROR in chemosensitivity of parental or docetaxel-resistant LAD cells.

Figure 1

(A) qRT-PCR assay was performed to examine the expression of linc-ROR after transfection of SPC-A1 or H1299 cells with linc-ROR (or control) and of SPC-A1/DTX or H1299/DTX cells with sh-ROR-1-4 (or sh-control). (B) IC50 values for docetaxel in SPC-A1 and H1299 cells transfected with linc-ROR and SPC-A1/DTX and H1299/DTX cells transfected with sh-ROR. (C, D) Flow cytometric analysis the influence of linc-ROR on apoptosis rate of SPC-A1/ROR cells or SPC-A1/DTX/sh-ROR cells. (E, F) Flow cytometric analysis the influence of linc-ROR on the cell cycle of SPC-A1/ROR cells or SPC-A1/DTX/sh-ROR cells. Error bars represent the mean ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01 vs. control group.