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. 2017 Mar 25;8(20):33144–33158. doi: 10.18632/oncotarget.16562

Figure 6. Function of linc-ROR in chemoresistance of LAD cells is partially reversed by miR-145.

Figure 6

(A) IC50 values of SPC-A1 and H1299 cells stably transfected with linc-ROR and SPC-A1/DTX and H1299/DTX cells stably transfected with sh-ROR was partially reversed by miR-145 mimics and miR-145 inhibitor, respectively. (B) Colony formation assays to determine the influence of miR-145 on linc-ROR. (C) Apoptosis rates of LAD cells lines were detected to determine the influence of miR-145 on linc-ROR. (D) Metastasis capacity of SPC-A1 and H1299 cells stably transfected with linc-ROR and SPC-A1/DTX and H1299/DTX cells stably transfected with sh-ROR was partially reversed by miR-145 mimics and miR-145 inhibitor, respectively. Error bars represent the mean ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01 vs. control group.