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. 2017 Apr 3;8(20):33444–33456. doi: 10.18632/oncotarget.16800

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Copyright: © 2017 Jiang et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A, B) pH2AX foci in MEFs from Fbxw7^+/+ (A) and Fbxw7^+/− (B) after MNU treatment. The cells were collected and fixed at the indicated time points after treatment. (C, D) The dynamics of pH2AX foci formation after treatment as shown in (A) and (B). Data are presented as mean ± SD, from three independent experiments. The X² or T test was used to determine the significance of pH2AX positive incidence and intensity. “*” refers to statistically significant (P < 0.05).