Figure 6. Loss of Fbxw7 expression and overexpression of c-Myc in gastric cancer.
(A) Western blot for pH2AX expression at indicated time points after MNU treatment (left). Genotyping and microscopic view of Fbxw7+/+ and Fbxw7+/− MEFs (right). (B, C) Western blot analyses were performed using total protein lysates extracted from antral mucosa from mice (B) and from patients (C).