Table 2. Relation of single nucleotide polymorphisms (SNPs) to coronary artery disease as determined by multivariable logistic regression analysis.
SNP | Dominant | Recessive | Additive 1 | Additive 2 | |||||
---|---|---|---|---|---|---|---|---|---|
P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | ||
rs58098972 | A/G | 0.0064 | 1.16 (1.04–1.29) | 0.2601 | 0.0118 | 1.15 (1.03–1.29) | 0.1780 | ||
rs77336780 | C/G (A304G) | 0.0355 | 0.90 (0.81–0.99) | 0.0145 | 0.74 (0.57–0.94) | 0.1381 | 0.0085 | 0.72 (0.55–0.92) | |
rs200121865 | G/C (G149A) | 0.0034 | 2.27 (1.32–3.86) | 0.0682 | 0.0065 | 2.16 (1.25–3.69) | 0.0679 | ||
rs202069030 | G/C (R51S) | 0.0099 | 0.32 (0.09–0.78) | ND | 0.0099 | 0.32 (0.09–0.78) | ND | ||
rs7188 | T/G | 0.5784 | 0.0009 | 0.76 (0.64–0.89) | 0.6171 | 0.0025 | 0.77 (0.65–0.91) | ||
rs2271395 | A/G (T1587A) | 0.0023 | 0.85 (0.77–0.94) | 0.0918 | 0.0084 | 0.86 (0.77–0.96) | 0.0052 | 0.82 (0.72–0.94) |
Multivariable logistic regression analysis was performed with adjustment for age, sex, and the prevalence of hypertension, diabetes mellitus, and dyslipidemia. Based on Bonferroni's correction, a P value of <9.92 × 10−5 (0.05/504) was considered statistically significant. OR, odds ratio; CI, confidence interval; ND, not determined.